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Public defence, Polymer synthesis technology, MSc Maryam Madani

Public defence from the Aalto University School of Chemical Engineering, Department of Chemical and Metallurgical Engineering.
Doctoral hat floating above a speaker's podium with a microphone.

Title of the thesis: Cationic and Zwitterionic Cellulose Derivatives: Synthesis, Properties, and Potential Applications

Thesis defender: Maryam Madani 
Opponent: Dr. Hannes Orelma, VTT
Custos: Assistant Prof. Jukka Niskanen, Aalto University School of Chemical Engineering

Cationic and zwitterionic cellulose derivatives: synthesis, properties, and potential applications

This doctoral thesis investigates the chemical modification of cellulose to develop advanced functional materials. Cellulose is a natural, abundant, biodegradable, and renewable biopolymer with significant potential for sustainable material design. The study focuses on the synthesis, characterization, and functional evaluation of modified cellulose derivatives, particularly cationic, zwitterionic, and oxidized cellulose materials. The purpose of the study was to design and understand functional cellulose-based materials with tailored properties for biomedical and technological applications. By introducing specific chemical functionalities into cellulose, the research aimed to enhance properties such as antimicrobial activity, ionic conductivity, biocompatibility, and mechanical performance.

The research produced several important results. Cationic cellulose nanocrystals demonstrated the ability to interact with viruses and bacteria through electrostatic interactions. Oxidized cellulose nanocrystals were shown to function as effective crosslinking agents in hydrogel networks, producing injectable, self-healing, and mechanically robust hydrogels suitable for wound-healing applications. In addition, cationic cellulose was incorporated into electrospun nanofiber mats to create antibacterial wound dressing materials. Finally, zwitterionic cellulose-based hydrogels were developed with ionic conductivity and flexibility suitable for wearable strain sensor applications.

The developed materials can potentially be applied in several fields, including biomedical devices, wound care, antimicrobial materials, environmental technologies, and wearable electronic sensor.
 
cationic cellulose, oxidized cellulose, zwitterionic cellulose, hydrogel, nanofiber mats, wearable sensors 

Thesis available for public display 7 days prior to the defence at .

Contact information: maryam.madani@aalto.fi

Doctoral theses of the School of Chemical Engineering

A large white 'A!' sculpture on the rooftop of the Undergraduate centre. A large tree and other buildings in the background.

Doctoral theses of the School of Chemical Engineering are available in the open access repository maintained by Aalto, Aaltodoc.

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